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REACTION BIOLOGY 与科瑞斯宣布联手拓展中国业务 - 云+社区 - 腾讯云
来自 : 发布时间:2024-12-25

苏州蚂蚁淘生物科技有限公司是专业从事生物技术产品销售的高科技企业,是国内生物试剂、仪器、消耗品领域的知名企业之一。起发公司自成立以来,连续2年高速成长。公司的发展目标是建成专业从事生物技术产品销售、生产与开发的一流公司。

Reaction Biology详细产品列表:

货号

产品

价格(美元)

HMT-11-376

ASH1L (His) Methyltransferase

325

DMT-21-124

DNMT1

450

DMT-21-125

DNMT3a Methyltransferase

450

DMT-21-126

DNMT3b

450

HMT-11-101

DOT1L Methyltransferase

395

HMT-25-115

EZH1 Complex

450

HMT-25-114

EZH2 Complex

799

HMT-25-173

EZH2-Y641F Complex

799

HMT-11-102

G9a Methyltransferase (GST) (aa 786-1210)

299

HMT-11-245

G9a Methyltransferase (His) (aa 913-1193)

299

HMT-12-104

G9a/GLP Complex Methyltransferase

325

HMT-11-103

GLP Methyltransferase Protein

299

HMT-15-105

MLL1 Complex

499

HMT-15-106

MLL2 Complex

499

HMT-15-107

MLL3 Complex

499

HMT-15-108

MLL4 Complex

499

MT-11-359

NNMT (GST) (Nicotinamide N-Methyltransferase)

299

MT-11-358

NNMT (His) (Nicotinamide N-Methyltransferase)

299

HMT-11-319

NRMT1 (GST)

325

HMT-21-139

NSD1 Methyltransferase

450

HMT-21-138 0

NSD2 (His) Methyltransferase

450

HMT-21-122

NSD2 Methyltransferase

550

HMT-11-377

NSD2 SET (His)

325

HMT-21-159

NSD2-E1099K Methyltransferase

599

HMT-11-378

NSD2-E1099K-SET (His)

325

HMT-21-181

NSD2-T1150A Methyltransferase

450

HMT-11-379

NSD2-T1150A-SET (His)

325

HMT-11-132

NSD3 Methyltransferase

325

HMT-21-348

PRDM2 Methyltransferase

325

HMT-21-152

PRDM9 Methyltransferase

450

HMT-11-119

PRMT1 Methyltransferase

325

HMT-11-113

PRMT3 Methyltransferase

325

HMT-11-120

PRMT4 Methyltransferase

399

HMT-21-172

PRMT5 Methyltransferase

450

HMT-22-434

PRMT5(C449S)/MEP50

799

HMT-22-148

PRMT5/MEP50 Complex

799

HMT-11-121

PRMT6 Methyltransferase (GST)

325

HMT-21-380

PRMT6 Methyltransferase (His)

325

HMT-21-382

PRMT7 (His)

450

HMT-11-135

PRMT8 Methyltransferase

325

MT-11-356

s-COMT (His) (Soluble Catechol-O-Methyltransferase)

299

MT-11-357

s-COMT (V108M) (His) (Soluble Catechol-O-Methyltransferase

299

HMT-15-116

SET1A Complex (5-subunits)

499

HMT-15-117

SET1B Complex (5-subunits)

499

HMT-11-133

SET7/9 Methyltransferase

299

HMT-11-476

SET8 (GST)

299

HMT-11-118

SET8 Methyltransferase

299

HMT-11-128

SETD2 (GST) Methyltransferase

299

HMT-11-129

SETD2 (His) Methyltransferase

299

HMT-11-110

SMYD2 Methyltransferase

325

HMT-11-111

SUV39H1 Methyltransferase

299

HMT-11-418

SUV39H2 (GST) Methyltransferase

299

HMT-11-112

SUV39H2 (His) Methyltransferase

299

HMT-21-149

SUV420H1-tv1 Methyltransferase

450

HMT-21-150

SUV420H1-tv2 Methyltransferase

450

HMT-21-349

SUV420H2 Methyltransferase

325

HMT-14-109

WRAD2

375

HMT-14-438

(H3.3-H4)2 Tetramer

325

HMT-35-435

Core Histones (Chicken)

250

HMT-11-184

Fibrillarin (GST)

325

HMT-11-183

Fibrillarin (His)

325

HMT-11-137

GST-GAR

299

HMT-12-316

H2A/H2B dimers

325

HMT-11-180

Histone H1.0

50

HMT-11-146

Histone H2A

50

HMT-11-147

Histone H2B

50

HMT-11-134

Histone H3.3

50

HMT-35-179

Nucleosomes (Chicken Mono/Di)

280

HMT-35-182

Nucleosomes (Chicken Oligo/Poly H5 Enriched)

280

Reaction Biology公司成立于2001年,是专门从事早期药物发现化验服务的公司,提供广泛的服务,包括用于激酶和表观遗传生物化学以及基于细胞的高通量筛选(HTS)和选择性化合物分析的稳定测定技术。我们还提供相关的HTS检测试剂,包括高度纯化和特征化的表观遗传蛋白。平均每年进行数百万次HTS和性能分析。在全球有超过750家公司(包括制药,生物技术,学术和非营利实验室)购买我们的产品。

Reaction Biology描述:

人类重组EZH2incomplexwithhumanrecombinantsEED.TotalcomplexMWis228.7kDa.Allproteinsarefull长度(residue2throughC末端)也是全美-expressedinaninsectcell / baculovirusexpressionsystem.TheEEDsubunitincorporatesanN-terminalStrepandFlag-tagandallothersincludeanN-terminalHis-tag.CatalyzesthetransferofmethylgroupsfromS腺苷-L-甲硫氨酸(SAM)tothee-aminofunctionofproteinL-lysineresidues,specificallylysine-27ofhistoneH3( H3K27)。在开发过程中,Polycomb Repressive Complex 2(PRC2)是主要的甲基转移酶对IBL的反应eforgeneratingtrimethylatedhistoneH3lysine-27(的H3K27me3),anepigeneticmarkessentialforprogrammedrepressionofgeneexpression1-5.EZH2,whichincludesaSETmethyltransferasedomain,isthecatalyticsubunitofPRC21,6.ThecoreofthecatalyticcomplexincludesEZH2,EED,SUZ12andRbAp48,whileadditionofAEBP2significantlyenhancesthemethyltransferaseactivityofthecomplex(> 3×)6.EZH2isoverexpressedinawiderangeofhumancancersanditsoverexpressioncancorrelatewithtumorprogression,increasedmetastasisandpoorprognosis(seereview7).DepletionofEZH2and / orotherPRC2componentscaninhibitgrowthorinduceapoptosisincancercells6,8-10.Consequently,EZH2isconsideredapromisingtargetforthedevelopmentofanti -癌症疗法11

存取编号:EZH2NM_001203247,EEDNM_003797,SUZ12NM_015355

包括酰胺酸EZH22-746,EED2-441,SUZ122-739

标记(S):EEDhasanN末端链霉菌标记标签,其他所有N末端His标签

分子量:228.7kDa

EXPRESSIONSYSTEM昆虫细胞/杆状病毒

SUPPLIEDAS:Solutionofpurifiedrecombinantproteinin20mMTris盐酸,pH8,150mMNaCl,2mMMgCl2,2mMDTT,20%甘油(w / v),0.01%NP-40asdeterminedbyOD280

储存:-70°C。在使用前应迅速融化并储存。应保留未使用的未稀释蛋白质,例如干燥/冰乙醇液中的氮。尽可能减少冻融/解冻,但不建议使用稀释体积太小(<5µl)的稀释蛋白质。

重要要推广的品牌Nanocs chromotek polysciences echelon-inc Bio-Rad,伯乐 , R&D Systems Millipore,密理博 Jackson NEBNew England Biolabs Sigma-Aldrich,西格玛奥德里奇, Athens Research & Technology Illumina , Tocris TwistDx Enzymatics ,酶科技,NovusThermothermofisher,赛默飞,赛默飞世尔,gibcoinvitrogen,英潍捷基,ambionebiosciencemolecular probesABIApplied BiosystemsThermo Scientificpierce

本文链接: http://reaction.immuno-online.com/view-1512937964.html

发布于 : 2024-12-25 阅读()